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Oxidative impairment of hippocampal long-term potentiation involves activation of protein phosphatase 2A and is prevented by ketone bodies.
Maalouf M, Rho JM. Maalouf M, et al. J Neurosci Res. 2008 Nov 15;86(15):3322-30. doi: 10.1002/jnr.21782. J Neurosci Res. 2008. PMID: 18646208 Free PMC article.
In the present study, we explored the effects of the KB acetoacetate (ACA) and beta-hydroxybutyrate (BHB) on impairment of hippocampal long-term potentiation (LTP) in rats by hydrogen peroxide (H(2)O(2)) using electrophysiological, fluorescence imaging, and enzyme assay te …
In the present study, we explored the effects of the KB acetoacetate (ACA) and beta-hydroxybutyrate (BHB) on impairment of hippocampal long- …
Lack of long-term histopathologic changes in brain and skeletal muscle of mice treated with a ketogenic diet.
Rho JM, Sarnat HB, Sullivan PG, Robbins CA, Kim DW. Rho JM, et al. J Child Neurol. 2004 Jul;19(7):555-7. J Child Neurol. 2004. PMID: 15526964
Although there is increasing awareness of adverse effects associated with use of the high-fat ketogenic diet, very little is known regarding its long-term clinical consequences, especially in relation to cardiovascular health. ...
Although there is increasing awareness of adverse effects associated with use of the high-fat ketogenic diet, very little is known regarding …